If the opponent doesn't have a creature
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In short, if some cards are more obviously powerful, everyone will play them
It's okay if any of them are already tapped, and it's okay if any of them are controlled by someone other than the defending player
The Color Red in Ice Age: Big Creatures and the Stolen Land to Cast Them The color Red had some huge creature additions in Ice Age, Balduvian hydra, Chaos Lord, Goblin Mutant an an Orgg wannabe and Marton Stromgald, but it also added some powerful spells such as Battle Frenzy, Pyroclasm, Jokulhaups, Conquer, Game of Chaos, Dwarven Armory and Incinerate
Now, you need payoffs to make all of this worth it