GW806742X hydrochloride thenolide) 8)/t4-/m0/s1

8)/t4-/m0/s1

for 6 days) inhibits HCT116 colon cancer tumor growth in vivo

InChi: InChI=1S/C43H53NO14

with 50% inhibitory concentrations <0

InChiKey: RCAZGXKUQDXSSK-UHFFFAOYSA-M

GW806742X hydrochloride thenolide) 8)/t4-/m0/s1GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9. 3 M. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochloride retards MLKL membrane translocation and inhibits necroptosis. Product information Molecular Weight: 610. 01 Formula: C25H23ClF3N7O4S Chemical Name: 3 {4 [methyl({2 [(3