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PubMed PMID: 31489149
The latest stage of development for LX7101 was a randomized
InChiKey: FWWMRDPEXYCBRS-UHFFFAOYSA-N
1401532-80-6 (SAG(cis）)
2016 Aug 17
N-Desmethyltamoxifen hydrochloride - CAS# 15917-65-4 0273 PubMed PMID: 31489149N Desmethyltamoxifen hydrochloride, CAS No. 15917 65 4, is the major metabolite of tamoxifen in humans. N Desmethyltamoxifen, a poor antiestrogen, is a ten fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. Product information CAS Number: 15917 65 4