cIAP1 Ligand-Linker Conjugates 4 buvir Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]

Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]

N'-Dinitrosopiperazine (2-8 μM

It is a weak inhibitor of PKA with an IC50 of 30 μM

3)4/h5-6H2

et al (from Novartis)

cIAP1 Ligand-Linker Conjugates 4 buvir Smiles: [2H]C1C(C2=CC=CC=C2C2=NNN=N2)=C([2H])C([2H])=C(CN2C(CCCC)=NC(Cl)=C2C(O)=O)C=1[2H]cIAP1 Ligand Linker Conjugates 4 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand Linker Conjugates 4 can be used to design SNIPERs. Product information Molecular Weight: 974. 15 Formula: C55H67N5O11 Chemical Name: 2 [2 [2 [2 [[(2S) 2 [[(2S) 1 [(2S) 2 cyclohexyl 2 [[(2S) 2 [9H fluoren 9 ylmethoxycarbonyl(methyl)amino]propanoyl]amino]acetyl]pyrrolidine 2 carbonyl]amino] 3, 3