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This agent is used to treat diarrhea-predominant irritable bowel syndrome in women only
is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity
the expression level of GABRA1
CAS Number: 1246638-08-3
InChiKey: QCZAWDGAVJMPTA-UHFFFAOYSA-N
PCNA-I1 Size:Contact [email protected] for quotation This agent is used toPCNA I1 is a selective inhibitor of proliferating cell nuclear antigen (PCNA, a potential anticancer target). PCNA I1 selectively binds to PCNA trimers with Kd of ~0. 2 to 0. 4 M. PCNA I1 inhibits the growth of tumor cells of various tissue types with IC50 of ~0. 2 M. PCNA I1 induces DNA damage and apoptosis in both LNCaP and PC 3 cells. PCNA I1 also induces autophagy in PC 3 cells. Product information CAS Number: 444930 42 1 Molecular Weight: 310. 37
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