Sorafenib - CAS# 284461-73-0 otarol 24)25)13(22)12(21)18-9/h5-6H

24)25)13(22)12(21)18-9/h5-6H

3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol hydrochloride

but reduces open probability by > 90% with Ki=0

Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry

Minglei Lu

Sorafenib - CAS# 284461-73-0 otarol 24)25)13(22)12(21)18-9/h5-6HSorafenib is a synthetic compound targeting growth signaling and angiogenesis. Sorafenib blocks the enzyme RAF kinase, a critical component of the RAF MEK ERK signaling pathway that controls cell division and proliferation; in addition, sorafenib inhibits the VEGFR 2 PDGFR beta signaling cascade, thereby blocking tumor angiogenesis. Sorafenib was approved in 2005 for use in the treatment of advanced renal cancer. Product information CAS Number: 284461