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InChi: InChI=1S/C18H16O4/c1-11(2)22-14-7-8-15-17(9-14)21-10-16(18(15)20)12-3-5-13(19)6-4-12/h3-11
The drug may be given orally or intravenously
MacMillan KS
Guanethidine monosulfate
DCLK1-IN-1 potently binds DCLK1 in HCT116 cells (IC50 = 279 nM)
Simvastatin acid ammonium tone Methyltransferase InChi: InChI=1S/C18H16O4/c1-11(2)22-14-7-8-15-17(9-14)21-10-16(18(15)20)12-3-5-13(19)6-4-12/h3-11Simvastatin ammonium is an active metabolite of simvastatin lactone mediated by CYP3A4 5 in the intestinal wall and liver (pKa=5. 5). Simvastatin ammonium reduces indoxyl sulfate mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene. Product information CAS Number: 139893 43 9 Molecular Weight: 453. 61 Formula: C25H43NO6 Synonym: Tenivastatin ammonium Chemical Name:
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