Tariquidar 60314 14(6):294-303

14(6):294-303

CAS Number: 80-08-0

Following DOT1L inhibition

3-d]pyrimidin-4-yl}-3-chloro-2-methylbenzene-1-sulfonamide

MSA-2 induced elevations of interferon-b in plasma and tumors by both routes of administration

Tariquidar 60314 14(6):294-303Tariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS