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the higher sensitivity of p53-deficient tumors toward GSK461364 could potentially offer an opportunity to treat tumors that are refractory to other chemotherapies as well as early line therapy for these genotypes
InChiKey: LQBVNQSMGBZMKD-UHFFFAOYSA-N
Local delivery of novel MRTF/SRFinhibitors prevents scar tissue formation in a preclinical model of fibrosis
InChiKey: KFHMLBXBRCITHF-UHFFFAOYSA-N
InChiKey: KINWYTAUPKOPCQ-YFKPBYRVSA-N
PI-103 butyric acid (4-PBA) the higher sensitivity of p53-deficientPI 103 is a potent, cell permeable, ATP competitive inhibitor of phosphatidylinositol 3 kinase (PI3K) family members with selectivity toward DNA PK, PI3K (p110), and mTOR. Product information CAS Number: 371935 74 9 Molecular Weight: 348. 36 Formula: C19H16N4O3 Synonym: PI103 PI 103 Chemical Name: 3 (4 morpholinopyrido[3',2': 4,5]furo[3,2 d]pyrimidin 2 yl)phenol Smiles: OC1C=C(C=CC=1)C1=NC2=C(OC3=NC=CC=C23)C(=N1)N1CCOCC1 InChiKey: TUVCWJQQGGETHL
US$ 118.95
US$ 129.95