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Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts
InChi: InChI=1S/C10H8BrNO/c1-6-5-8(11)10(13)9-7(6)3-2-4-12-9/h2-5
InChiKey: DGFYECXYGUIODH-UHFFFAOYSA-N
Lenalidomide treatment blocks CLL cell-induced T cell actin synapse dysfunction
which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors
Osimertinib D6 - CAS# 1638281-44-3 n 15 Antitumor activity of sphingosine kinaseOsimertinib D6 (AZD 9291 D6) is a deuterium labeled Osimertinib. Osimertinib is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R T790M, respectively. Product information CAS Number: 1638281 44 3 Molecular Weight: 505. 64 Formula: C28H33N7O2 Synonym: AZD 9291 D6 Mereletinib D6 Chemical Name: N [2 ({2 [di(H)methylamino]ethyl}(methyl)amino) 4 methoxy 5 {[4 (1 methyl 1H indol 3 yl)pyrimidin 2
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