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Almotriptan Malate Catalog No.:M9101-2 Smiles: COC1=CC(O)=CC=C1OCCNCC(O)COC1C=CC=C2NC3C=CC=CC=3C=12

SKU: 70317592134

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Description

Smiles: COC1=CC(O)=CC=C1OCCNCC(O)COC1C=CC=C2NC3C=CC=CC=3C=12

Epub 2013 Feb 4

InChiKey: YSTVFDAKLDMYCR-NDEPHWFRSA-N

CAS Number: 182004-65-5

In the mouse xenograft models using subcutaneously transplanted UM-UC-14 and MGHU3

Almotriptan Malate Catalog No.:M9101-2 Smiles: COC1=CC(O)=CC=C1OCCNCC(O)COC1C=CC=C2NC3C=CC=CC=3C=12Almotriptan Malate is a triptan drug discovered and developed by Almirall for the treatment of heavy migraine headache. Almotriptan is a Serotonin 1b and Serotonin 1d Receptor Agonist. Binding of the drug to the receptor leads to vasoconstriction of the cranial blood vessels and thus affects the redistribution of cranial blood flow. Almotriptan significantly increases cerebral blood flow and reduces blood flow through extracerebral cranial vessels.

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