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YM155 significantly inhibits endogenous survivin expression in PC-3 and PPC-1 human HRPC cells with deficient p53 through transcriptional inhibition of the survivin gene promoter
Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility
Smiles: ONC(=O)/C=C/C1C=CC(CN(CCO)CCC2=CNC3=CC=CC=C23)=CC=1
also known as AFN-12520000
New agents for prostate cancer
Dalfopristin 280 YM155 significantly inhibits endogenous survivinDalfopristin (RP54476) is a semi synthetic analogue of ostreogyrcin A. Quinupristin dalfopristin (Q D) is a parental streptogramin with a spectrum of activity that includes Gram positive pathogens, including those resistant to other classes of antimicrobial compounds. Product information CAS Number: 112362 50 2 Molecular Weight: 690. 85 Formula: C34H50N4O9S Synonym: RP54476 Chemical Name: (12Z,32S,33R,6R,7R,8E,13E,15E,17S) 33 ((2