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TAK-960 dihydrochloride 31156 N-(4-chlorophenyl)-1-{N-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido}methanimidamide

SKU: 7252524443

4.1
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Description

N-(4-chlorophenyl)-1-{N-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido}methanimidamide

Odoroside A is an active ingredient extracted from the leaves of Nerium oleander Linn

CAS Number: 1357072-61-7

NSC-253272

Lai Yee Cheong

TAK-960 dihydrochloride 31156 N-(4-chlorophenyl)-1-{N-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido}methanimidamideTAK 960 dihydrochloride is an orally available, selective inhibitor of polo like kinase 1 (PLK1), with an IC50 of 0. 8 nM. TAK 960 dihydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16. 9 and 50. 2 nM, respectively. TAK 960 dihydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts. Product information Molecular Weight: 634. 52 Formula:

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