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SKF-96365 hydrochloride Size:2mg solid (1998) Bioorg Med Chem Lett

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Description

(1998) Bioorg Med Chem Lett

Etoposide phosphate induces cell cycle arrest

CI-1033 also shows high permeability in Caco-2 cells and inhibits secretory transport of vinblastine

and attenuates tau hyperphosphorylation and neurofibrillary tangles (NFT) formation via promoting protein phosphatase 2A (PP2A) activity

Suppression of Plk1 in vivo by using GSK461364 results in mitotic arrest with aberrant mitotic figures consisting of monopolar or collapsed mitotic spindles

SKF-96365 hydrochloride Size:2mg solid (1998) Bioorg Med Chem LettSKF 96365 hydrochloride is a potent TRP channel blocker and a store operated Ca2+ entry (SOCE) inhibitor. SKF 96365 hydrochloride significantly inhibits hERG, hKCNQ1 hKCNE1, hKir2. 1 and hKv4. 3 current, and significantly prolongs the QTc interval in isolated guinea pig hearts. SKF 96365 hydrochloride exhibits potent anti neoplastic activity by inducing cell cycle arrest and apoptosis in colorectal cancer cells. Product information CAS Number: 130495

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