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hSMG-1 inhibitor 11e DE-IN-2 25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21

SKU: 72955639683

4.2
USD100.00 USD136.00

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Description

25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21

for 24 hours) shows substantial bactericidal activity against S

0 M Sucrose solutions less during HE-feeding relative to chow-feeding (P=0

Formula: C23H25ClN2O

Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites

hSMG-1 inhibitor 11e DE-IN-2 25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21hSMG 1 inhibitor 11e is a potent and selective hSMG 1 kinase inhibitor with an IC50 of <0. 05 nM. hSMG 1 inhibitor 11e shows >900 fold selectivity over mTOR (IC50 of 45 nM), PI3K (IC50s of 61 nM and 92 nM) and CDK1 CDK2 (IC50s of 32 M and 7. 1 M). Product information CAS Number: 1402452 10 1 Molecular Weight: 517. 60 Formula: C26H27N7O3S Chemical Name: 1 {4 [4 (2 {[3 (dimethylsulfamoyl) 4 methylphenyl]amino}pyrimidin 4 yl)pyridin 2 yl]phenyl} 3

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