![EA4 Catalog No.:M22641-C Smiles: C[C@]12C=CC3[C@@H](CCC4=CC(=O)CCC4=3)[C@@H]1CC[C@@H]2O](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M22641_1635327789.gif?v=1635327790)
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Smiles: C[C@]12C=CC3[C@@H](CCC4=CC(=O)CCC4=3)[C@@H]1CC[C@@H]2O
(2012) Anticancer Drugs
InChiKey: MFFMDFFZMYYVKS-SECBINFHSA-N
InChi: InChI=1S/C31H36N4O6
Chemical Name: (2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(2-methyl-1
EA4 Catalog No.:M22641-C Smiles: C[C@]12C=CC3[C@@H](CCC4=CC(=O)CCC4=3)[C@@H]1CC[C@@H]2OKi: 130 M EA4 is a rPLA2 inhibitor. rPLA2, a calcium dependent cytosolic phospholipase A2 (cPLA2), was initially isolated and characterized from bovine and human red blood cells. With a molecular mass of 42 kDa, cPLA2 shows biochemical properties similar to cPLA2 Type IV. In vitro: It was found that EA4 was able to inhibit a Ca(2+) ionophore induced arachidonic acid release from both human and bovine red blood cells, demonstrating that this enzyme was