Futibatinib Catalog No.:M18482-C Ritalinic acid (α-phenylpiperidine-2-acetic acid) is

Ritalinic acid (α-phenylpiperidine-2-acetic acid) is a substituted phenethylamine and an inactive major metabolite of the psychostimulant drugs methylphenidate

and M5076 sarcoma

4 are 20 min-1 and 77 µM

as assessed by hematoxylin and eosin and anti-K14 histological staining at the study end

and/or liver cell necrosis

Futibatinib Catalog No.:M18482-C Ritalinic acid (α-phenylpiperidine-2-acetic acid) isFutibatinib (TAS 120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3. 9, 1. 3, 1. 6, and 8. 3 nM for FGFR 1 4, respectively. Futibatinib inhibits mutant and wild type FGFR2 with similar IC50s (wild type FGFR2=0. 9 nM; V5651=1 3 nM; N550H=3. 6 nM; E566G=2. 4 nM). Product information CAS Number: 1448169 71 8 Molecular Weight: 418. 45 Formula: C22H22N6O3 Chemical Name: 1 [(3S) 3 {4 amino 3 [2 (3,5