Ribociclib D6 327romantadine Smiles: OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1

Smiles: OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1

InChi: InChI=1S/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H

AMG319 achieves this coverage at the 3 mg/kg level

Leuthner B

corresponding to 3 × IC50) decreases the number of MHC+ cells and increased the number of nuclei per cell

Ribociclib D6 327romantadine Smiles: OC(=O)[C@H]1CN(CCCP(O)(O)=O)CCN1Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4 6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000 fold less potent against the cyclin B CDK1 complex. Product information CAS Number: 1328934 40 2 Molecular Weight: 440. 57 Formula: C23H30N8O Chemical Name: 7 cyclopentyl N,N di(H)methyl 2 {[5 (piperazin 1 yl)pyridin 2 yl]amino} 7H pyrrolo[2,3 d]pyrimidine 6 carboxamide