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stimulates reactive oxygen species (ROS) formation and mitochondrial membrane depolarization
is distinguished by minimal toxicity to bone marrow cells at concentrations active against RB1mut cancer cells
PD-1/PD-L1-IN-NP19 exhibits much lower activity for inhibiting mouse PD-1/PD-L1 interaction with an IC50 in the micromolar range (>1µM)
AG14361 markedly enhances NSC 362856 activity against LoVo xenografts and delays tumor growth when combined with NSC 362856
Smiles: CN1CCC(COC2=CN=C(N=C2)C2=CC(CN3N=C(C=CC3=O)C3=CC(=CC=C3)C#N)=CC=C2)CC1
3-O-Methyltolcapone D7 tolactam I stimulates reactive oxygen species (ROS)3 O Methyltolcapone D7 (Ro 40 7591 D7) is a deuterium labeled 3 O Methyltolcapone. 3 O Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood brain barrier, and can be used for treatment of Parkinson's disease. Product information Molecular Weight: 294. 31 Formula: C15H13NO5 Chemical Name: 2 methoxy 4 [4 (H)methyl(2,3,5,6 H)benzoyl] 6 nitrophenol Smiles:
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