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Savolitinib c Acid PubMed Central PMCID: PMC6780662

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Description

PubMed Central PMCID: PMC6780662

1-4H3/t14-

Isox-Cha-Chg-NH2

BAY11-7082 was used at 10-20 µM final concentration in various assays

Rosuvastatin (3 mg/kg) daily administration for 14 days decreases plasma cholesterol levels by 26% in male beagle dogs with normal cholesterol levels

Savolitinib c Acid PubMed Central PMCID: PMC6780662Savolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0

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