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TPI-1 inhibits the growth of B16 melanoma tumors in mice at a tolerated oral dose in a T cell-dependent manner but has little effects on B16 cell growth in culture
CAS Number: 300586-90-7
Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster
which may result in decreased tumor cell proliferation and migration
Smiles: COC1C=CC(=CC=1)OCC1C2=CC(OC)=C(C=C2CCN1C(=O)C1=CC(Cl)=CC=C1)OC
Alda-1 - CAS# 349438-38-6 size:2mg solid TPI-1 inhibits the growth ofAlda 1, CAS No. 349438 38 6, is a potent and selective Aldehyde Dehydrogenase 2 Agonist. Alda 1 reverses alcohol induced hepatic steatosis and cell death in mice. Alda 1 inhibits atherosclerosis and attenuates hepatic steatosis in apolipoprotein E knockout mice. Alda 1 reduces cerebral ischemia reperfusion injury in rat through clearance of reactive aldehydes. Pharmacological activation of ALDH2 by Alda 1 reversed alcoholic steatosis and apoptosis
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