2-chloro-3-Deazaadenosine eimide SH-SY5Y cells) attenuates the paraquat-induced

SH-SY5Y cells) attenuates the paraquat-induced accumulation of reactive oxygen species (ROS) and attenuates the paraquat-induced expression of apoptotic proteins

Epub 2012 Apr 5

These IC50 values are similar to the value obtained with chicken Src (20 nM)

enhances cholesterol 7α-hydroxylase (CYP7A1) activity

Formula: C6H12ClN3O3

2-chloro-3-Deazaadenosine eimide SH-SY5Y cells) attenuates the paraquat-induced2 chloro 3 Deazaadenosine, a stable analog of adenosine, is an agonist for adenosine receptors . Adenosine receptors are members of G protein coupled receptors (GPCRs). Extracellular adenosine acts as a local modulator with a generally cytoprotective function in the body. Extracellular adenosine has been implicated in increasing the ratio of oxygen supply to demand, protecting against ischaemic damage by cell conditioning, triggering anti inflammatory