1A-116 16454 3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2

3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2

Ro 64-6198

Smiles: CC(=O)N1CCN(CC1)C1=CC(OC)=C(C=C1)NC1=NC(NC2=CC(=CC=C2)NC(=O)C=C)=C(C=N1)C(F)(F)F

which are conserved among TLR8/antagonist structures

InChi: InChI=1S/C52H69N13O11/c1-3-32(2)43(50(73)74)64-48(71)42-17-11-25-65(42)49(72)41(27-36-29-56-31-59-36)62-46(69)39(60-47(70)40(26-33-18-20-37(66)21-19-33)61-44(67)35-14-9-22-55-28-35)15-7-8-23-57-45(68)38(16-10-24-58-51(53)54)63-52(75)76-30-34-12-5-4-6-13-34/h4-6

1A-116 16454 3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-21A 116 is a Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer, such as breast cancer. 1A 116 prevents Rac1 regulated processes involved in the primary tumorigenesis and metastastic processes . Product information CAS Number: 1430208 73 3 Molecular Weight: 307. 31 Formula: C16H16F3N3 Chemical Name: N' (3,5 dimethylphenyl) N [2 (trifluoromethyl)phenyl]guanidine Smiles: CC1=CC(=CC(C)=C1)NC(=N)NC1=CC=CC=C1C(F)(F)F