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(R)-5-Hydroxymethyl Tolterodine 2 inhibitor 1 O[C@H]1CCCN[C@@H]1CC(=O)CN1C=NC2=CC(Br)=C(Cl)C=C2C1=O

SKU: 84404142236

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Description

O[C@H]1CCCN[C@@H]1CC(=O)CN1C=NC2=CC(Br)=C(Cl)C=C2C1=O

InChi: InChI=1S/C20H28O5/c1-9-7-19-10(2)5-13-14(18(13

which is probably responsible for many of its unique properties

Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer

3-benzothiazol-2-yl)-1-phenylurea

(R)-5-Hydroxymethyl Tolterodine 2 inhibitor 1 O[C@H]1CCCN[C@@H]1CC(=O)CN1C=NC2=CC(Br)=C(Cl)C=C2C1=ODesfesoterodine, also known as PNU 200577, is a major pharmacologically active metabolite of tolterodine, a new muscarinic receptor antagonist intended for the treatment of an overactive bladder. In vitro, PNU 200577 produced a competitive and concentration dependent inhibition of carbachol induced contraction of guinea pig isolated urinary bladder strips (KB = 0. 84 nM; pA2 = 9. 14). In vivo, PNU 200577 was significantly more potent at inhibiting

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