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Tournoux A
Smiles: CC(C)S(=O)(=O)C1=CC2C(C=C1)=NC=CC=2NC1C=C2N=CSC2=CC=1
7(8):1447-52
Schoene NW
3390/toxins8030078
L-2-Hydroxyglutaric acid disodium 0302 Tournoux AL 2 Hydroxyglutaric acid disodium ((S) 2 Hydroxyglutaric acid disodium, L 2 Hydroxyglutarate disodium, LGA, L 2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. L 2 Hydroxyglutaric acid disodium is also an inhibitor of mitochondrial creatine kinase (Mi CK) with Km and Ki of 2. 52 mM and 11. 13 mM, respectively. Product information CAS Number: 63512 50
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