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14R)-4-ethenyl-3-hydroxy-2
2017 Jan 8
Telatinib significantly inhibits ABCG2-mediated transport of [3H]-E₂17βG in ABCG2 overexpressing membrane vesicles
De Haven Brandon A
InChi: InChI=1S/C42H56N2O10/c1-7-33(31-27-38(49-4)40(51-6)39(28-31)50-5)41(45)44-18-9-8-13-34(44)42(46)54-35(16-14-29-15-17-36(47-2)37(25-29)48-3)30-11-10-12-32(26-30)53-24-21-43-19-22-52-23-20-43/h10-12
I-BET282 ts-2 14R)-4-ethenyl-3-hydroxy-2I BET282 is a pan inhibitor of all eight BET bromodomains, and selectivity over other representative bromodomain containing proteins. I BET282 shows pIC50s ranging 6. 4 7. 7 for BRD2 (BD1 BD2), BRD2 (BD1 BD), BRD3 (BD1 BD), and BRD4 (BD1 BD). Product information CAS Number: 1422554 34 4 Molecular Weight: 450. 53 Formula: C25H30N4O4 Chemical Name: 4 {8 methoxy 1 [(2R) 1 methoxypropan 2 yl] 2 (oxan 4 yl) 1H imidazo[4,5 c]quinolin 7 yl} 3,5 dimethyl 1,2
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