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Approximately 75% more tumor cells exhibited apoptotic changes in the 100 mg/kg treatment group compared with vehicle control group at 8 h after dosing
CID-53347902
InChiKey: FPZLLRFZJZRHSY-HJYUBDRYSA-N
Remdesivir-metabolite
Chemical Name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol hydrochloride
R406 free base Catalog No.:M10764-10 Approximately 75% more tumor cellsTamatinib, also known as R 406, is a potent inhibitor of Syk with IC50 of 41 nM. R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin PF4 complex directed antibodies. R406 blocks fc receptor signaling and reduces immune complex mediated inflammation. R406 inhibited phosphorylation of Syk substrate linker for activation of T cells in mast cells and B cell linker protein SLP65 in B cells. R406 bound to the ATP
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