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Smiles: CN(C)CCN(C)C1=CC(OC)=C(C=C1N)NC1=NC(=CC=N1)C1=CN(C)C2=CC=CC=C12
25-dihydroxycholecalciferol in vitamin D-deficient rats
Smiles: CC1C=C2C(=CC=1)N=CC(C(=O)OCC)=C2NC1C=CC(=CC=1)N(CC)CC
Baharuldin MT
InChiKey: MOVYITHKOHMLHC-UHFFFAOYSA-N
TRPC6 inhibitor l Estradiol Smiles: CN(C)CCN(C)C1=CC(OC)=C(C=C1N)NC1=NC(=CC=N1)C1=CN(C)C2=CC=CC=C12SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7 mediated Ca(2+) influx into cells with IC50 s of 9. 5, 282 and 226 nM, whereas TRPC4 and TRPC5 mediated Ca(2+) entry was not affected. Product information CAS Number: 1333207 63 8 Molecular Weight: 440. 79 Formula: C21H24Cl3N3O Chemical Name: 4