K-Ras G12C-IN-2 MG 837 Smiles: CCN(CCC)C(=O)C1=CC2=CC=C3C(NC=C(C3=O)[N+]([O-])=O)=C2N=C1

Smiles: CCN(CCC)C(=O)C1=CC2=CC=C3C(NC=C(C3=O)[N+]([O-])=O)=C2N=C1

and is not associated with changes in PGE2

Smiles: N#C/C(=C1/SC[C@H](S/1)C1=CC=C(Cl)C=C1Cl)/N1C=NC=C1

Thirunarayanan N

Chemical Name: 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonamide

K-Ras G12C-IN-2 MG 837 Smiles: CCN(CCC)C(=O)C1=CC2=CC=C3C(NC=C(C3=O)[N+]([O-])=O)=C2N=C1K Ras G12C IN 2 is an irreversible covalent K Ras G12C inhibitor. Product information CAS Number: 1629267 75 9 Molecular Weight: 418. 92 Formula: C21H27ClN4O3 Chemical Name: 1 [3 (4 {2 [(4 chloro 5 cyclopropyl 2 hydroxyphenyl)amino]acetyl}piperazin 1 yl)azetidin 1 yl]prop 2 en 1 one Smiles: C=CC(=O)N1CC(C1)N1CCN(CC1)C(=O)CNC1=CC(C2CC2)=C(Cl)C=C1O InChiKey: LTHUJAPYGTUVMD UHFFFAOYSA N InChi: InChI=1S C21H27ClN4O3 c1 2 20(28)26 12 15(13 26)24 5 7 25(8 6