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TAK-683 exhibits an IC50 value (95% CI) from receptor binding assays is 150-180 pM and EC50 value (95% CI) from Ca+ mobilization assays is 180 (159–203) pM in rat KISS1R-expressing Chinese hamster ovary (CHO) cells
17-dien-22-one
levels of HBeAg in serum
When Hesperadin concentration was 1 μM
including myeloma
R 1485 dihydrochloride 8400 TAK-683 exhibits an IC50 valueProduct information Molecular Weight: 450. 35 Formula: C18H22Cl2FN3O3S Chemical Name: 4 (2 fluorobenzenesulfonyl) 8 (piperazin 1 yl) 3,4 dihydro 2H 1,4 benzoxazine dihydrochloride Smiles: Cl. Cl. O=S(=O)(C1=CC=CC=C1F)N1CCOC2=C(C=CC=C12)N1CCNCC1 InChiKey: SNXURKRGPYXWRN UHFFFAOYSA N InChi: InChI=1S C18H20FN3O3S. 2ClH c19 14 4 1 2 7 17(14)26(23,24)22 12 13 25 18 15(5 3 6 16(18)22)21 10 8 20 9 11 21;; h1 7,20H,8 13H2; 2*1H Technical Data Appearance:
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