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11-trihydroxy-1
77 μM and more than 100-fold selectivity over other GRKs
CAS Number: 1050480-30-2
Formula: C17H16ClN3O
625 µM for p300)
Almotriptan o cholesterol 11-trihydroxy-1Almotriptan is a 5 HT1B 1D receptor agonist used to treat migraine. IC50: Target: 5 hydroxytryptamine1B 1D (5 HT1B 1D) ReceptorAlmotriptan is a selective 5 hydroxytryptamine1B 1D (5 HT1B 1D) receptor agonist, used for the treatment of Migraine attacks in adults. Almotriptan showed low nanomolar affinity for the 5 HT(1B) and 5 HT(1D) receptors in several species, including the human, while affinity for 5 HT receptors other than 5 HT(1B 1D) was clearly