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and Solubility
THAL-SNS-032 consists of a CDK-binding SNS-032 ligand linked to a thalidomide
which may yield a potential cancer therapeutic by targeting the survivin protein directly
InChiKey: HQHUIUQMQXUPHI-UHFFFAOYSA-N
J Clin Invest
PROTAC BET degrader-2 EE788 and SolubilityPROTAC BET degrader 2 is a highly potent degrader of Bromodomain and Extra Terminal (BET) proteins with an IC50 value of 9. 6 nM in cell growth inhibition in the RS4; 11 cells and capable of achieving tumor regression. Product information CAS Number: 2093388 33 9 Molecular Weight: 770. 84 Formula: C41H42N10O6 Chemical Name: 4 [(3 cyclopropyl 1 ethyl 1H pyrazol 5 yl)amino] 7 (3, 5 dimethyl 1, 2 oxazol 4 yl) N {3 [2 (2, 6 dioxopiperidin 3 yl) 1 oxo 2, 3