Amiloride Size:Solid 10 mg Targeting p75NTR signalling using LM11A-31

Targeting p75NTR signalling using LM11A-31

a ～3- to 4-fold increase in potency as an agonist for N- and P/Q-type Ca2+ channels

It modulates the coupling of Smo with its downstream effector by interacting with the Smo heptahelical domain (KD = 59 nM)

thus attenuating phosphorylation of the Aurora substrate H3S10

dose-dependent reduction of phosphorylation of FGFR4 signaling pathway components

Amiloride Size:Solid 10 mg Targeting p75NTR signalling using LM11A-31Amiloride is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver. In the USA, this drug is available via prescription only. Product information CAS Number: 2609 46 3 Molecular Weight: 229. 63 Formula: C6H8ClN7O Chemical Name: 3,5 diamino N carbamimidoyl 6 chloropyrazine 2 carboxamide Smiles: NC1=NC(N)=C(N=C1Cl)C(=O)NC(N)=N InChiKey: XSDQTOBWRPYKKA UHFFFAOYSA N