Azido-PEG2-C2-sulfonic acid 511ethysticin Smiles: CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

Smiles: CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=O

PI3K δ and PI3K β

1) ligand that induces recruitment of β-arrestin2 (pEC50 of 8

Formula: C20H19F6N7O2

53 L/h/kg) following oral administration (10 mg/kg) in male Sprague-Dawley rats

Azido-PEG2-C2-sulfonic acid 511ethysticin Smiles: CC[C@H](C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(N)=OAzido PEG2 C2 sulfonic acid is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 1817735 39 9 Molecular Weight: 239. 25 Formula: C6H13N3O5S Chemical Name: 2 [2 (2 azidoethoxy)ethoxy]ethane 1 sulfonic acid Smiles: [N ]=[N+]=NCCOCCOCCS(O)(=O)=O InChiKey: GBEOYHHTRHXIRM UHFFFAOYSA N InChi: InChI=1S C6H13N3O5S c7 9 8 1 2 13 3 4 14 5 6 15(10,11)12 h1 6H2,(H,10,11,12) Technical Data Appearance: Solid