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Smiles: CCN1C(=NC2C=CC(=CC=2)S(N)(=O)=O)SC=C1C1=CC=C(Cl)C=C1Cl
1-2H3/b11-6+
28-trioxa-20
5-dihydro-1H-pyrrole-1-carboxamide
yet blocks the agonist-induced conformational changes in TM6
PARP14 inhibitor H10 - CAS# 2084811-68-5 515C144 hydrochloride Smiles: CCN1C(=NC2C=CC(=CC=2)S(N)(=O)=O)SC=C1C1=CC=C(Cl)C=C1ClPARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (24 fold over PARP1). PARP14 inhibitor H10 induces caspase 3 7 mediated cell apoptosis. Product information CAS Number: 2084811 68 5 Molecular Weight: 557. 58 Formula: C24H27N7O7S Chemical Name: 3 ({2 [4 (2 {3 [(3 carbamoylphenyl)carbamoyl]propanamido}ethyl) 1H 1, 2, 3 triazol 1 yl]ethyl}sulfamoyl)benzoic acid Smiles:
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