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STO-609 inhibits constitutively active CaM-KKα as well as the wild-type enzyme
CHEMBL2397100
Chemical Name: 5-methyl-N-[4-(trifluoromethyl)phenyl]-1
2)36)28(39-5)26(34)17-12(32)7-14(37-3)19(21(16)17)20-15(38-4)8-13(33)18(23(20)22)27(35)29(24)40-6/h7-8
Solubility: DMSO : 250 mg/mL (600
AKBA Catalog No.:M8389-2 STO-609 inhibits constitutively active CaM-KKαAKBA is an antiangiogenic and neuroprotective agent, reducing the impact of proliferative retinopathies, protecting neurons against ischemic injury involving the Nrf2 HO 1 pathway. AKBA is a naturally occurring pentacyclic triterpene isolated from the gum resin exudate from the stem of the tree B. serrata (frankincense). It selectively inhibits 5 lipoxygenase (IC50 = 1. 5 M) in an enzyme directed, nonredox, and noncompetitive manner. 2 3 acetyl 11