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EHT 1864 specifically inhibits glucose-induced Rac1 activation and membrane association and associated downstream signaling events culminating in inhibition of GSIS
and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices
2-dihydro-[3
Formula: C5H6N6
InChiKey: WOHRHWDYFNWPNG-UHFFFAOYSA-N
Fezolinetant HCl Size:10 mg solid EHT 1864 specifically inhibits glucose-inducedFezolinetant, also known as ESN 364, is Neurokinin 3 (NK 3) receptor antagonist which has been optimized for use in womens health, and is being developed for sex hormone related disorders such as endometriosis, polycystic ovarian syndrome and uterine fibroids. Fexolinetant allows modulation of the hypothalamic pituitary gonadal axis with a selective action on hormones relevant to disease. The agent is expected to have greater tolerability than
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