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Vatalanib also inhibits the growth and metastasesof several human carcinomas in nude mice without significant effect on circulating blood cells or bone marrow leukocytes
is a selective inhibitor of Glutaminase GLS1 (KGA)
1374356-45-2
InChiKey: PLGQWYOULXPJRE-FFPZBHEPSA-N
17-pentaazacycloicosane-4-carboxamide acetate
TPT-260 dihydrochloride - CAS# 2076-91-7 llardiine Vatalanib also inhibits the growthTPT 260 2HCl, also known as R55, is a thiophene thiourea derivative with molecule weight 260. 00 in free base form. There is no formal name yet, we temporally call this molecule as TPT 260. TPT260 acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~ 5 M). In cultured hippocampal neurons, TPT 260 dose dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of