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AKT-IN-6 Catalog No.:M32827-C Levistolide A Induces Apoptosis via

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Description

Levistolide A Induces Apoptosis via ROS-Mediated ER Stress Pathway in Colon Cancer Cells

PubMed PMID: 24243015

CRS400393 (Compound 43) shows no obvious effect on CYP2B6 and CYP3A4

peripheral blood and bone marrow specimens from patients with leukemia and mitogenically (phytohemagglutinin) or antigenically (mixed lymphocyte culture) stimulated human peripheral blood cultures

Carboxyatractyloside dipotassium is a toxic natural product

AKT-IN-6 Catalog No.:M32827-C Levistolide A Induces Apoptosis viaAKT IN 6 (Example 13) is a potent Akt inhibitor. AKT IN 6 inhibits Akt1, Akt2 and Akt3 with IC50s < 500nM, respectively. (patent WO2013056015A1). Product information CAS Number: 1430056 54 4 Molecular Weight: 389. 43 Formula: C22H20FN5O Chemical Name: 5 {2 [(2S) 1 amino 3 (3 fluorophenyl)propan 2 yl] 1 oxo 2,3 dihydro 1H isoindol 5 yl} 1 methyl 1H pyrazole 4 carbonitrile Smiles: CN1N=CC(C#N)=C1C1=CC2CN([C@H](CN)CC3=CC(F)=CC=C3)C(=O)C=2C=C1 InChiKey:

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