ISA-2011B udesmol TAK-828F shows excellent RORγt isoforms

TAK-828F shows excellent RORγt isoforms selectivity (>5000-fold selectivity against human RORα and RORβ)

5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})-9H

Smiles: OC1C=C2O[C@@H]([C@H](O)[C@@H](C3=C4O[C@@H]([C@H](O)[C@H](C4=C(O)C=C3O)C3=C4O[C@@H]([C@H](O)CC4=C(O)C=C3O)C3=CC(O)=C(O)C=C3)C3=CC(O)=C(O)C=C3)C2=C(O)C=1)C1=CC(O)=C(O)C=C1

Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours

Molecular Weight: 2315

ISA-2011B udesmol TAK-828F shows excellent RORγt isoformsISA 2011B is a PIP5K1 inhibitor with promising anticancer effects . Product information CAS Number: 1395347 24 6 Molecular Weight: 423. 85 Formula: C22H18ClN3O4 Chemical Name: (2S,8S) 2 (5 chloro 1H indol 3 yl) 6 methyl 13,15 dioxa 3,6 diazatetracyclo[8. 7. 0. 0,. 0,]heptadeca 1(17),10,12(16) triene 4,7 dione Smiles: CN1CC(=O)N2[C@@H](CC3=CC4OCOC=4C=C3[C@H]2C2=CNC3=CC=C(Cl)C=C32)C1=O InChiKey: FSEZESVJDPKRDS UWJYYQICSA N InChi: InChI=1S C22H18ClN3O4