Pay in 4 interest-free payments of $28.75 Learn more
Ships within 48 hours · Estimated delivery Jul 30 - Aug 4
Smiles: COCCOC1=CC2=NC=NC(NC3=CC(=CC=C3)C#C)=C2C=C1OCCO
also known as BMS-512148
Smiles: NC1=NC(Cl)=NC2=C1N=CN2[C@H]1C[C@H](O)[C@@H](CO)O1
THAL-SNS-032 is a selective CDK9 degrader
24)34-20/h6
PRX-08066 - CAS# 866206-54-4 411575 (isomer 3) Smiles: COCCOC1=CC2=NC=NC(NC3=CC(=CC=C3)C#C)=C2C=C1OCCOPRX 08066 is a a novel 5 hydroxytryptamine receptor 2B antagonist, reduces monocrotaline induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. In the 5 HT(2B) expressing SI NET cell line, KRJ I, PRX 08066 inhibited proliferation (IC(50) 4. 6 x 10( 9)M) and 5 HT secretion (6. 9 x 10( 9)M) and decreased ERK1 2 phosphorylation and profibrotic growth factor synthesis and secretion (transforming growth factor beta 1 [TGFbeta1],