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stabilizes the inactive state of the complex
44(9):1456-66
efficacy in a rodent postoperative pain model
Exherin TFA salt
InChiKey: VBGNJMUEMDYZJJ-HGKIGUAWSA-N
Platensimycin e chloride hydrate stabilizes the inactive state ofPlatensimycin is an antibiotic produced by S. platensis that inhibits gram positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0. 1 M). Platensimycin targets the ketoacyl acyl carrier protein synthase I II, FabF B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S. aureus and E. coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
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