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Formula: C26H23F4N9O
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
is a Syk inhibitor with IC50 of 41 nM in a cell-free assay
115(9):2186-2191
InChi: InChI=1S/C19H13F3N4O3S2/c1-29-16-8-11(19(20
AM 404 Catalog No.:M22857-C Formula: C26H23F4N9OAM 404 is a selective inhibitor of anandamide transport . Also, it is an agonist of CB1 cannabinoid receptor and potential vanilloid type 1 (TRPV1). The endocannabinoid transporter (eCBT) is a transporter for the endocannabinoid. The blockade of anandamide transport has anti nociceptive effects. AM 404 is a selective anandamide transport inhibitor. AM404 inhibited anandamide transport with IC50 values of 1 and 5 M in neurons and astrocytes,