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Odanacatib dose-dependently reduces CTx release with an IC50=9
) protects bone and cartilage from degradation
Schonherr C
CAS Number: 1009820-21-6
Molecular Weight: 266
SD70 - Histone Demethylase JMJD2 Inhibitor. CAS# 332173-89-4 size:2 mg solid Odanacatib dose-dependently reduces CTx releaseSD70, CAS No. 332173 89 4, is a potent, selective and cell permeable inhibitor of histone demethylase JMJD2 (KDM4C), identified by phenotypic screening for inhibitors of ligand and genotoxic stress induced translocations in prostate cancer cells. Through Chem seq approach, SD70 was found to inhibit the androgen dependent AR program and prostate cancer cell growth, acting, at least in part, by functionally inhibiting the Jumonji domain containing
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