To address the rad-elephant in the room, the rules of mutate itself just didn't map well to the creation of mutants in Fallout humans as well as animals (non-humans) experience mutation
There are also cards with Flashback, Foretell, Rebound, Suspend, Retrace, and more for even more value
The legendary artifact four-drop is Halfling-able, nasty
However, Esior, Wardwing Familiar and Ardenn, Intrepid Archaeologist make an incredible team, and deserve more recognition as an exceptional Equipment-based pair
Basically, by opening boxes on release day (or release weekend), we can take advantage of the excitement for the new cards (new demand) and the fact that the freshly opened cards haven't had time to reach the market yet (lack of supply)
Sometimes the +1/+1 counter bonus is better than the static +1/+1, as it persists even when Dionus is not around