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Pikachu ex could get in quick enough to stop it reaching this explosive attack, but the only other real counter to Mewtwo ex was the similarly powerful Charizard ex, which struggled to gain traction in the meta for other reasons, and Mewtwo ex itself

Include the transformed land in creature-based token decks because you get green mana equivalent to the number of creatures you control

Diablo, Devoted Herald works best while exerted

There are also rats with infect, which toxic stacks with, allowing those creatures to dole out more than one poison counter each turn

However, weirdly enough, its also sometimes the best card against soft graveyard hate like Relic of Progenitus and Soul-Guide Lantern, as you can quickly rebuild a graveyard to fuel a Murktide Regent if your opponent has exiled your graveyard earlier in the game