Clozapine Catalog No.:M10647-2 CAS Number: 119615-63-3

CAS Number: 119615-63-3

CAS Number: 1883545-52-5

he 50% inhibitory concentration (IC50) of RO3280 for acute leukemia cells was between 74 and 797 nM

Treatment of cells with SB202190 significantly inhibits both basal and anti-Fas antibody-induced MAPKAPK 2 activity in a dose-dependent manner as measured in immune complex kinase assays with GST-hsp27 as a substrate

cell cycle arrest and induction of mitochondrial-mediated apoptosis

Clozapine Catalog No.:M10647-2 CAS Number: 119615-63-3Clozapine is an atypical antipsychotic drug because it binds to serotonin as well as dopamine receptors. Clozapine is a partial agonist at the 5 HT1A subunit of the serotonin receptor, putatively improving depression, anxiety, and the negative cognitive symptoms associated with schizophrenia. A direct interaction of clozapine with the GABAB receptor has also been shown. GABAB receptor deficient mice exhibit increased extracellular dopamine levels and