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The inhibition of USP7 is predicted to destabilize HDM2 and stabilize p53
GSK1014802
Smiles: CN1[C@@H]2CC(C[C@H]1CC2)OC(=O)[C@H](CO)C1C=CC=CC=1
Formula: C25H35NO3
InChi: InChI=1S/C16H13ClO4S/c17-15-7-3-13(4-8-15)11-22(20
IPR-803 ofistularin-3 The inhibition of USP7 isIPR 803 is a potent inhibitor of the uPARuPA protein protein interaction (PPI). IPR 803 binds directly to uPAR with sub micromolar affinity. IPR 803 displays anti tumor activity. Product information CAS Number: 892243 35 5 Molecular Weight: 453. 49 Formula: C27H23N3O4 Chemical Name: 3 {[12 (azepan 1 yl) 8 oxo 15 oxa 14 azatetracyclo[7. 6. 1. 0,. 0,]hexadeca 1(16),2,4,6,9,11,13 heptaen 10 yl]amino}benzoic acid Smiles: