That could be a card like Davriels Withering, which perpetually gives a creature -1/-2 if that card reduces a creature to 0 toughness or less and sends it to the graveyard, for example, the debuff will remain in effect even if a player is able to bring it back to battlefield (causing it to immediately die again)
I can see him gaining a lot of value in a Brago, King Eternal deck or even Alesha, Who Smiles at Death, re-using any of your other creatures' sweet ETB triggers
Let me know in the comments, or head over to our Discord if thats more your thing
Eight mana isn't cheap, but the ability is worth it
When a person has ten poison counters, they lose the game
Just make sure one of those enchantments is Solemnity to keep everything coming back as often as you need