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Poor Unfortunate Souls offers a little extra board control by removing threats before they can act, and once you have the board, Casa Madrigal will generate passive lore each turn while you continue to remove your opponent's characters through efficient trades
Before we talk about ROI, you need to understand why these cardboard rectangles hold value at all
It lets you cast creatures at instant speed, for energy, most of which in an energy deck will get you more energy
Once you need to pull off more complex plays, you may want to turn it off entirely or override it in some specific spots with Full Control, whenever you want to make sure things go exactly as you want
Until the advent of land cycling creatures, Krosan Tusker and Explosive Vegetation seemed like the only feasible solutions to get a third color of mana in a draft